Research Paper Volume 14, Issue 19 pp 7794—7823

Multifaceted investigation underlies diverse mechanisms contributing to the downregulation of Hedgehog pathway-associated genes INTU and IFT88 in lung adenocarcinoma and uterine corpus endometrial carcinoma


Figure 1. Evaluation of the prognostic significance of INTU mRNA level in different cancer types. Pan-cancer survival analysis was carried out to determine the relationship between INTU mRNA level and OS probabilities in 21 different types of cancer. Decreased INTU expression was found associated with poor prognosis in EAC, ESCC, KIRP, LUAD, PDAC, SARC and UCEC patients, whilst high level of INTU correlated with poor prognosis in LIHC and LUSC patients.