Research Paper Volume 14, Issue 20 pp 8221—8242
AR12 increases BAG3 expression which is essential for Tau and APP degradation via LC3-associated phagocytosis and macroautophagy
Figure 1. Control data showing protein expression knock down and protein over-expression. Left: BV2 and HCN2 cells as indicated were transfected with siRNA molecules to knock down the expression of the indicated proteins or transfected with plasmids to over-express the indicated proteins. The percentage remaining after knock-down or the percentage over-expression above basal levels is indicated. (n = 3 +/-SD) (total ERK2 is included as an invariant total protein loading control). Right: Images of HCN2 cells transfected to express TAU or APP.