Research Paper Volume 14, Issue 23 pp 9445—9457
Ganglioside GD1a enhances osteogenesis by activating ERK1/2 in mesenchymal stem cells of Lmna mutant mice
Figure 2. Osteogenic analysis in Lmna dysfunction MSCs compared to normal MSCs. (A) Alizarin Red staining. (B) Expression of osteogenic genes in Lmna dysfunction MSCs compared with normal MSCs. (C) Expression of osteogenic proteins in Lmna dysfunction MSCs compared with normal MSCs. (D) Lamin A/C knock down by siRNA. and (E) Alizarin Red staining. (F) Expression of osteogenic proteins in Lmna dysfunction MSCs compared with normal MSCs. (G) Expression of osteogenic genes in Lmna dysfunction MSCs compared with normal MSCs. ***p < 0.001 indicates a significant difference from the normal MSCs.