Research Paper Volume 14, Issue 23 pp 9679—9698

SKA1 promotes tumor metastasis via SAFB-mediated transcription repression of DUSP6 in clear cell renal cell carcinoma

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Figure 5. Analysis of the mRNA profiles of SKA1 knockdown and control 786-O cells. (A) Volcanic maps show the distribution of different genes between the sh-SKA1 and sh-Ctrl group. (B) Cluster diagrams show the aggregation of all samples and different genes at the expression level. (C) qRT-PCR analysis of DUSP6 mRNA expression in tumor and non-tumor renal tissues. (D) Kaplan-Meier curves for overall survival based on DUSP6 expression in ccRCC patients from TCGA-KIRC dataset (N = 516).