Research Paper Volume 15, Issue 1 pp 119—133

Profiling of a novel circadian clock-related prognostic signature and its role in immune function and response to molecular targeted therapy in pancreatic cancer

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Figure 4. Association of the circadian clock-related gene signature with intra-tumor immune infiltrates. (A) Radar plot showed no apparent switch between the low- and the high-risk cohorts. (B) Bubble chart revealed that CD8 T cell and B cell were critically negatively correlated with the hazard. (C) Box plot demonstrated that CD8 T cell, B cell, and neutrophils were significantly switched between the high-risk patients than in the low-risk patients.