Research Paper Volume 15, Issue 7 pp 2450—2459

Figure 4. FKBP11 significantly increases the apoptosis in osteosarcoma cells and affects the MAPK pathway. (A) Apoptosis was measured with an apoptosis kit. (B) Protein expression of cleaved caspase-3 was measured through western blotting after transfection of MG63 and 143B cells with Si-NC and Si-FKBP11 for 48 h. (C–E) The protein expression of p-MEK, MEK, p-ERK, and ERK in MG63 and 143B cells was measured by western blotting. ^*P < 0.05, ^**P < 0.01, and ^***p < 0.001.