Research Paper Volume 15, Issue 6 pp 1918—1930

Haplotype-GGGT in long non-coding RNA MALAT1 inhibits brain metastatic lung cancer and lymph nodes of lung cancer via the MALAT1/miR-328/KATNB1

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Figure 5. The luciferase activities of MALAT1 and KATNB1 were suppressed by miR-328 in A549 and H460 cells (*p value < 0.05 compared with control group). (A) Sequence analysis indicated the binding of miR-328 to MALAT1. (B) The luciferase activity of wild type MALAT1 was suppressed by miR-328 in A549 cells. (C) The luciferase activity of wild type MALAT1 was suppressed by miR-328 in H460 cells. (D) Sequence analysis indicated the binding of miR-328 to KATNB1. (E) The luciferase activity of wild type KATNB1 was suppressed by miR-328 in A549 cells. (F) The luciferase activity of wild type KATNB1 was suppressed by miR-328 in H460 cells.