Research Paper Volume 15, Issue 4 pp 947—981

Aging and memory are altered by genetically manipulating lactate dehydrogenase in the neurons or glia of flies

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Figure 6. Graphical summary dLdh level was altered in neurons or glia in the brain of flies. Long-term courtship memory (LTM) was reduced in aged flies by increasing neuronal dLdh and decreasing neuronal or glial dLdh. Survival was reduced by increasing glial dLdh and decreasing neuronal or glial dLdh.