Research Paper Volume 15, Issue 5 pp 1603—1614

Cytokine profiles of plasma extracellular vesicles as progression biomarkers in Parkinson’s disease

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Figure 1. (A) Baseline and follow-up plasma extracellular vesicle (EV)-derived cytokine profiles of people with Parkinson’s disease (PwP) and healthy controls (HCs). Representative protein blot images of cytokines: interleukin (IL)-1β, IL-6, IL-10, tumor necrosis factor (TNF)-α, and transforming growth factor (TGF)-β. Heat-shock protein 70 was the protein loading control. (BF) Comparison of plasma EV-derived IL-1β (B), TNF-α (C), IL-6 (D), IL-10 (E), and TGF-β (F) levels of PwP and HCs at baseline and follow-up. Data are presented as a dot plot with median values and first and third quartiles. Abbreviation: n.s.: nonsignificant.