Research Paper Volume 15, Issue 5 pp 1652—1667

ANGPTL2 promotes VEGF-A synthesis in human lung cancer and facilitates lymphangiogenesis

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Figure 6. ANGPTL2 promotes tumor growth and lymphangiogenesis in vivo. (AC) CL1-0 and CL1-5 cells were subcutaneously injected into the right flanks of BALB/c-nu mice. Four weeks later, the mice were sacrificed and the tumors were excised and weighed (n=5). (D) Tumor sections were immunostained using ANGPTL2, LYVE-1 and VEGF-A antibodies. *p < 0.05 compared with controls.