Research Paper Volume 15, Issue 6 pp 1977—2004
Hsp22 pretreatment protects against LPS-induced hippocampal injury by alleviating neuroinflammation and apoptosis by regulating the NLRP3/Caspase1/IL-1β signaling pathway in mice
Figure 5. Effect of Hsp22 on LPS-induced activation of NLRP3/Caspase-1/IL-1β pathways in BV2 Microglial Cells. (A) Cell Modeling Flowchart. (B) The protein band of Hsp22 and its expression (*p < 0.05 vs. Control; ns: p > 0.05, LPS vs. LPS+OE-Control; #p < 0.05 vs. LPS+OE-Control). (C–E) The protein band of NLRP3, Caspase-1, IL-1β and its expression. (**p < 0.01, *p < 0.05, **p < 0.01 vs. Control; ns: p > 0.05, LPS vs. LPS+OE-Control; ##p < 0.01, #p < 0.05, ##p < 0.01 vs. LPS+OE-Control).