Research Paper Volume 15, Issue 6 pp 2097—2114

ADAMTS1 induces epithelial-mesenchymal transition pathway in non-small cell lung cancer by regulating TGF-β

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Figure 1. ADAMTS1 is up-regulated in non-small cell lung cancer tumor tissues. (A) qRT-PCR was conducted the mRNA expression of ADAMTS1 in NSCLC tumor tissues than that in adjacent normal tissues. (B, C) Western blot was used for evaluating the protein expression of ADAMTS1 in NSCLC tumor tissues and adjacent normal tissues with different clinical grades (n=12). (D, E) The expression of ADAMTS1 was detected in NSCLC tissues and adjacent normal tissues, (scale bar=100 μm). *P<0.05, **P<0.01.