Research Paper Volume 15, Issue 6 pp 2308—2320
Curcumin (CUMINUP60®) mitigates exercise fatigue through regulating PI3K/Akt/AMPK/mTOR pathway in mice
Figure 4. Schematic diagram of the anti-fatigue mechanism of curcumin. Curcumin intervention was shown to improve energy metabolism and reduce the accumulation of metabolic waste by regulating AMPK and PI3k/AKT-mTOR. LA: lactic acid, MG: muscle glycogen, GS: glycogen synthase.