Research Paper Volume 15, Issue 9 pp 3249—3272

Exogenous exposures shape genetic predisposition to lipids, Alzheimer’s, and coronary heart disease in the MLXIPL gene locus

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Figure 2. Univariate associations of minor alleles of four SNPs from the MLXIPL gene with AD and CHD in two samples drawn from US cohorts (A) and UK biobank (B). Only one association of rs17145750 with AD was significant in the UK biobank. The Y-axis shows the effect sizes (beta) of the associations of each SNP with the respective outcomes. The X-axis shows SNPs for which association is shown. The vertical solid lines indicate 95% confidence intervals (CIs). Asterisks indicate different levels of significance, i.e., *5 × 10−4p < 0.05.