Research Paper Volume 15, Issue 8 pp 2863—2876

Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform

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Figure 4. PandaOmics TargetID scoring approach for potential targets selected according to strategy 1 (A), strategy 2 (B) and strategy 3 (C). Target hypotheses are ranked according to the scores obtained from different AI-powered predictive models: omics-, text-, key opinion leaders (KOLs) and funding- based. For each target additional information on tissue specific expression, accessibility by small molecules and antibodies, safety, novelty, structure availability, development level and protein family are provided. For a detailed description of all scores and filters see Materials and Methods section, as well as the user manual at https://insilico.com/pandaomics/help.