Research Paper Volume 15, Issue 9 pp 3465—3479

Figure 2. PA enhanced the effect of miR-143-5p in promoting the EMT of ARPE-19 cells. (A) miR-143-5p expression in ARPE-19 cells was determined via quantitative PCR; n = 3 for each group. (B) Protein expression of E-cadherin, Fibronectin, α-SMA, Snail, and Vimentin protein levels in ARPE-19 cells transfected with NC or miR-143-5p mimics (n = 3 for each group). (C) Protein expression of E-cadherin, Fibronectin, α-SMA, Snail, and Vimentin in ARPE-19 cells transfected with NC or miR-143-5p inhibitors (n = 3 for each group). (D) Migration of ARPE-19 cells after the overexpression of miR-143-5p inhibitors or/and PA treatment (n = 3 for each group). (E) Expression of E-cadherin, Fibronectin, α-SMA, Snail, and Vimentin in ARPE-19 cells after the overexpression of miR-143-5p inhibitors or/and PA treatment (n = 3 for each group). ^*P < 0.05, ^**P < 0.01, and ^***P < 0.001, as compared with the indicated group.