Research Paper Volume 15, Issue 9 pp 3621—3634
Ling Zhi-8, a fungal immunomodulatory protein in Ganoderma lucidum, alleviates CPT-11-induced intestinal injury via restoring claudin-1 expression
Figure 4. Beneficial effects of LZ-8 on body weight loss in mice with CPT-11-induced intestinal injury. Relative weight was calculated for each animal relative to its weight on day 4. There were no apparent changes of body weight profiles in the control and LZ groups, but body weights decreased significantly in mice of the CPT and LZ+CPT groups. The decline in body weights was milder in mice of the LZ+CPT group than the CPT group. One-way ANOVA was used for statistical analysis. * indicates P < 0.05, compared with the control group; # indicates P < 0.05, compared with the CPT group. n = 5 mice/group.