Research Paper Volume 15, Issue 12 pp 5887—5916

Swertia cincta Burkill alleviates LPS/D-GalN-induced acute liver failure by modulating apoptosis and oxidative stress signaling pathways

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Figure 8. ESC alleviated acute liver failure within an in vivo model. (A) Liver index; (B) serum ALT activity, (C) AST activity, (D) TP levels, (E) ALB levels, (F) SOD levels, (G) MDA levels, (H) CAT levels, (I) GSH levels, (J) IL1-β levels, (K) IL-6 levels, and (L) TNF-α levels; (M) The histopathology of mice liver (HE 400×); (N) Necrosis score; (O) inflammation degree score. Results of 6 independent experiments were described above, of which the significant ones were recorded as *p < 0.05, **p < 0.01 and #p < 0.05, ##p < 0.01, respectively, for the model group and the control group.