Research Paper Volume 15, Issue 15 pp 7408—7423
Senescence-related gene c-Myc affects bladder cancer cell senescence by interacting with HSP90B1 to regulate cisplatin sensitivity
Figure 3. Screening for the best senescence-related prognostic genes in bladder cancer. (A) Expression of CCN1, IRF5, MYC, POU5F1, and TGFB1I1 in bladder cancer I+II (n=132), III (n=140), and IV (n=134). (B) Expression of CCN1, IRF5, MYC, POU5F1, and TGFB1I1 in bladder cancer high-grade samples (n=384) and low-grade samples (n=21). (C) Single-factor Cox regression analysis of prognostic differences among factors. (D) Multi-factor Cox regression analysis of prognostic differences among factors. (E) Columnar plots showing survival at 1, 3, and 5 years for the construct models. (F) Nomogram curves showing calibration curves for survival at 1, 3, and 5 years for the construct models.