Research Paper Volume 15, Issue 21 pp 11918—11939

The development and experimental validation of hypoxia-related long noncoding RNAs prognostic signature in predicting prognosis and immunotherapy of cutaneous melanoma

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Figure 1. Risk model construction based on the HRLs prognostic signature in CM. (A) LASSO regression analysis shows the optimal coefficients and minimum lambda. (B) Risk score distribution, and the scatter dot plot shows the correlation between risk score and survival time in CM. (C) Kaplan-Meier survival curve analysis suggests that the OS rate of patients with low-risk score is longer than those with high-risk score. (D) Principal component analysis illustrates a significant separation between low- and high-risk group. (E) Heatmap diagram shows the expression of 5 prognostic HRLs of patients in the low- and high-risk group.