Research Paper Volume 15, Issue 22 pp 13010—13040

Identification of topoisomerase 2A as a novel bone metastasis-related gene in liver hepatocellular carcinoma

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Figure 6. Correlation analysis between TOP2A expression and pathways and markers related to metastasis or proliferation using TCGA database. (AC) Spearman correlation analysis between TOP2A and PI3K-AKT-mTOR pathway, EMT markers, and tumor proliferation signature. (D) Spearman correlation analysis between the expression level of TOP2A and VEGFA, MMP2, and MMP9.