Research Paper Volume 15, Issue 22 pp 13163—13175
Hypoxia-regulated exosomes mediate M2 macrophage polarization and promote metastasis in chondrosarcoma
Figure 5. Schematic model of hypoxic exosomes promoting macrophage polarization and chondrosarcoma cell metastasis. Chondrosarcoma cell-derived hypoxic exosomes mediate macrophage M2 polarization and thereby facilitate the migration of chondrosarcoma cells.