Research Paper Volume 15, Issue 23 pp 13753—13775

PBRM1 mutation and WDR72 expression as potential combinatorial biomarker for predicting the response to Nivolumab in patients with ccRCC: a tumor marker prognostic study

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Figure 6. The correlation between the expression of WDR72 and FOXP3, CD8, CPT1A in advanced ccRCC tumor tissues. (A) H&E staining and IHC staining showing expression of WDR72, FOXP3, CD8 and CPT1A in advanced ccRCC tumor tissues. (BD) Spearman correlation analysis of IHC scores of WDR72 and FOXP3 (B), WDR72 and CD8 (C), as well as WDR72 and CPT1A (D). Abbreviations: FOXP3, Forkhead Box Protein 3; H&E staining, hematoxylin-eosin staining; IHC, immunohistochemistry.