HACE1 expression in heart failure patients might promote mitochondrial oxidative stress and ferroptosis by targeting NRF2

Peiyi Yin; Yongbin Wu; Xiang Long; Shuqiang Zhu; Shiwei Chen; Feng Lu; Kun Lin; Jianjun Xu

doi:doi:10.18632/aging.205272

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Research Paper Volume 15, Issue 23 pp 13888—13900

HACE1 expression in heart failure patients might promote mitochondrial oxidative stress and ferroptosis by targeting NRF2

Figure 6. NRF2 is one target for HACE1 in model of heart failure. Microarray analysis (A–C), NRF2 mRNA expression (D–F), NRF2 and GPX4 protein expressions (G, H) GPX4 protein expressions in blot (I). ##p<0.01 compared with model+vector group or control group or si-nc group.