Research Paper Volume 16, Issue 16 pp 11824—11842

Identifying novel circadian rhythm biomarkers for diagnosis and prognosis of melanoma by an integrated bioinformatics and machine learning approach

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Figure 7. Construction and validation of the prognostic model. (A) Heatmap of key CRG expression and related risk score ranking and survival status distribution of patients. (B) Kaplan-Meier curves comparing high- and low-risk groups in the TCGA-melanoma cohort. (C) ROC curves of the prognostic model for predicting 3-, 5- and 10-year overall survival in TCGA-melanoma cohort. (D) Kaplan-Meier survival curve analysis in GSE65904 dataset. (E) ROC curves of the prognostic model for predicting 3-, 5- and 10-year overall survival in GSE65904 dataset.