Figure 3 — Single-cell sequencing technology to characterize stem T-cell subpopulations in acute T-lymphoblastic leukemia and the role of stem T-cells in the disease process

Research Paper|Volume 16, Issue 20|pp. 13117–13131

Single-cell sequencing technology to characterize stem T-cell subpopulations in acute T-lymphoblastic leukemia and the role of stem T-cells in the disease process

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Figure 3.Construction of a differentiation trajectory from Stem T cells to Naive T cells 1. (A) Differentiation trajectory from Stem T cells to Naive T cells 1 was constructed using Monocle 3. (B) Scatterplot of the expression levels of the genes of interest as a function of pseudotime. (C) Differentiation trajectory from Stem T cells to Naive T cells 1 constructed with Monocle 2. (D) Heatmap of the expression level of the gene of interest with pseudotime.