Research Paper Volume 16, Issue 22 pp 13588—13607

Impaired renal transporter gene expression and uremic toxin excretion as aging hallmarks in cats with naturally occurring chronic kidney disease

Figure 3. Uremic toxins in healthy senior cats. Healthy cats in cohort 1 were divided into two groups: those less than 12 years of age (YNG), and those aged 12 years or older (OLD). (A–E) The box and bars indicate means and SEM. P-values from the Mann-Whitney test are presented as asterisks: *P < 0.05. (F, G) Spearman’s correlation analysis between cat’s age and log concentration of TMAO and IxS, respectively. P-value and correlation coefficient are indicated in the plot.