Research Paper Advance Articles
The aspartate superpathway in gut microbiota-related metabolic pathways mediates immune cell protection against COPD and IPF: a Mendelian randomization analysis
Figure 3. Forest plot shows the causal effect of each single SNP on total IPF risk. The horizontal axis is employed to quantify the magnitude of the impact exerted by the exposure factor on the outcome, whereas the vertical axis denotes single-nucleotide polymorphisms (SNPs). A negative value implies that the exposure may decrease the risk of the outcome’s occurrence, while a positive value suggests that the exposure may elevate the risk of the outcome’s occurrence. The inverse-variance weighted (IVW) method is utilized to assess validity, and the Mendelian randomization Egger (MR Egger) method is applied to detect and correct for potential horizontal pleiotropy.