Research Paper Volume 17, Issue 6 pp 1544—1570
Implications of the KHDC4-TRAF2 axis in the context of prostate cancer prognosis
Figure 4. Shared gene ontology between TRAF2 and KHDC4 is associated with adverse prognosis outcomes. (A) A Venn diagram analysis collecting molecules positively or negatively correlated to TRAF2 in TCGA-PRAD datasets (Cell 2015, Firehose Legacy, and PanCancer Atlas). (B) Graphical abstract illustrating the potential biological roles influenced by TRAF2 in prostate cancer. (C) Canonical pathways affected by TRAF2-related molecules. (D) Molecular links to TRAF2 regulations in prostate cancer. (E) The correlation of KHDC4 and TRAF2 individually with Progression-Free Interval (PFI) and Disease-Free Interval (DFI) in TCGA-PRAD. (F) The correlation of Progression-Free Interval (PFI) and Disease-Free Interval (DFI) in TCGA-PRAD with the combined distribution of KHDC4 and TRAF2.