Research Paper Volume 17, Issue 7 pp 1721—1745

Association of DNA methylation age acceleration with digital clock drawing test performance: the Framingham Heart Study

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Figure 2. Comparison of effect size in the association between DNAm age acceleration and the dCDT total score. DNAm age acceleration was obtained by regressing DNAm metrics on chronological aging, followed by standardization with a mean of zero and SD of one. We conducted an association analysis between the dCDT total score and standardized DNAm age acceleration. CI, confidence interval.