Research Paper Advance Articles
Establishment of an optimized chemotherapy-induced mouse model for premature ovarian failure: protocol and findings
Figure 3. Three weeks post-induction, follicle counts were analyzed in CTX/Bu-treated mice, using Cyclophosphamide (CTX: 80, 100, 120, 120 mg/kg) in combination with Busulfan (Bu: 15, 20, 12, 30 mg/kg). This design enabled dose-dependent assessment of ovarian follicular depletion in the POF mode.