Research Paper Advance Articles

Establishment of an optimized chemotherapy-induced mouse model for premature ovarian failure: protocol and findings

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Figure 7. POF failure (POF) in NMRI female 6-8 weeks mice. Dose-response of ovarian follicles destruction by Cyclophosphamide (CTX: 80, 100, 120mg/Kg) and Busulfan (Bu: 15, 20, 12, 30 mg/Kg) for 4 weeks, observed at different magnifications (4× = 40×, 10× = 100×).