Research Paper Advance Articles
CD47 antisense oligonucleotide treatment improves glucose homeostasis and alleviates dyslipidemia in aged male mice
Figure 2. CD47 ASO treatment improved glucose homeostasis and hyperlipidemia in aged male mice. (A) Fasting glucose levels were measured after 6 hrs fasting and glucose tolerance test (GTT) was performed. AUC (area under curve of GTT) was shown; (B) Fasting insulin levels, Insulin tolerance test (ITT) and AUC of ITT were shown; (C) HOMA-IR was calculated; (D) Plasma free fatty acid, total cholesterol, and triglycerides levels were measured. Data are represented as mean ± SEM (n = 6) mice/group). *P < 0.05 and **P < 0.01 compared to control ASO group.