Research Paper Advance Articles
CD47 antisense oligonucleotide treatment improves glucose homeostasis and alleviates dyslipidemia in aged male mice
Figure 3. CD47 ASO treatment reduced adipocytes size of visceral fat by suppressing lipogenesis. (A) Representative H&E staining image of peri-renal white adipose tissue (pWAT) (scale bar = 100 μm); (B) Frequency of adipocytes size of pWAT; (C) Gene expression in pWAT by qPCR; (D) FASN protein expression level by immunoblotting and quantification; (E) Inflammatory and macrophage markers gene expression in pWAT by qPCR. (F). PKG1 protein expression level by immunoblotting and quantification. Data are represented as mean ± SEM (n = 6 mice/group). *P < 0.05 and **P < 0.01 compared to control ASO group.