Research Paper Advance Articles

Figure 2. The association between TB and epigenetic age in the TwinsUK and KORA cohort samples. Scatter plots of the GrimAge acceleration residuals (top left, primary analysis B = −1.576, p = 3.99 × 10⁻⁶) and epigenetic estimate of telomere length, DNAmTL (top right, primary analysis B = 0.036, p = 0.003), in the discovery TwinsUK sample of 509 females. Bottom row plots show results for the KORA sample of 1,160 individuals for GrimAge acceleration residuals (bottom left, primary analysis B = −1.06, p = 7.2 × 10⁻⁶) and DNAmTL (bottom right, primary analysis B = 0.022, p = 0.007).