Research Paper Volume 17, Issue 12 pp 2950—2988
Age-specific DNA methylation alterations in sperm at imprint control regions may contribute to the risk of autism spectrum disorder in offspring
Figure 4. Island content of CpGs within 450K array and age-associated DMCs. (A) Percentages of CpGs by island content are displayed with respect to the 450K (n = 482,287). (B) Percentages of CpGs by island content are displayed with respect to the number of significant age-related DMCs (n = 14,622). (C–E) By DNA methylation subgroup (Abbreviations: UM: unmethylated, mean β-value <0.2; HM: hemi-methylated, 0.20 ≤ mean β-value ≤0.80; FM: fully methylated, mean β-value>0.80).