Research Paper Volume 17, Issue 12 pp 2950—2988

Figure 7. Comparison of our set of age-related DMCs with earlier published datasets. Venn diagram showing the number of genes that have been identified by different authors as being differentially methylated by age in sperm; starting from a recent review by Bernhardt et al. [11], where 2,355 genes have been selected. Next to our results, the following publications have been included in this comparison: Bernhardt et al., Jenkins et al., Laurentino et al., and Oluwayiose et al. [9–12]. Seven genes (center of diagram) were identified by at least four studies (DLGAP2, SLC22A18AS, C7orf50, UTS2R, BEGAIN, GRIN1, and PCDH15); two are known imprinted genes (DLGAP2 and SLC22A18AS).