Research Paper Volume 18 pp 234—260

A manually curated gene–phenotype catalogue for progeroid syndromes and premature aging

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Protein–protein interaction (PPI) network of proteins encoded by genes associated with progeroid syndromes, highlighting prioritized hub proteins. Hubs, defined as the top ten nodes ranked by node degree, are shown in red, representing proteins with a high number of interaction partners and central positions within the network topology.