Volume 1, Issue 1

Aging: past, present and future

Mikhail V. Blagosklonny, Judith Campisi, David A. Sinclair,

https://doi.org/10.18632/aging.100009 pp 1—5

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Longevity regulation in flies: A role for p53

Lawrence A. Donehower,

https://doi.org/10.18632/aging.100010 pp 6—8

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Breathing lessons: Tor tackles the mitochondria

Toren Finkel,

https://doi.org/10.18632/aging.100013 pp 9—11

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Sirtuins at the Breaking Point: SIRT6 in DNA Repair

David B. Lombard,

https://doi.org/10.18632/aging.100014 pp 12—16

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Apolipoprotein D in lipid metabolism and its functional implication in atherosclerosis and aging

German Perdomo, H. Henry Dong,

https://doi.org/10.18632/aging.100004 pp 17—27

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Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A

Phillip R. Musich, Yue Zou,

https://doi.org/10.18632/aging.100012 pp 28—37

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dSir2 and Dmp53 interact to mediate aspects of CR-dependent life span extension in D. melanogaster

Johannes H. Bauer, Siti Nur Sarah Morris, Chengyi Chang, Thomas Flatt, Jason G. Wood, Stephen L. Helfand,

https://doi.org/10.18632/aging.100001 pp 38—48

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Young adult donor bone marrow infusions into female mice postpone age-related reproductive failure and improve offspring survival

Kaisa Selesniemi, Ho-Joon Lee, Teruko Niikura, Jonathan L. Tilly,

https://doi.org/10.18632/aging.100002 pp 49—57

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Dual regulation of TERT activity through transcription and splicing by ΔNP63α

Esther Vorovich, Edward A. Ratovitski,

https://doi.org/10.18632/aging.100003 pp 58—67

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Fat accumulation in Caenorhabditis elegans triggered by the electrophilic lipid peroxidation product 4-Hydroxynonenal (4-HNE)

Sharda P. Singh, Maciej Niemczyk, Ludwika Zimniak, Piotr Zimniak,

https://doi.org/10.18632/aging.100005 pp 68—80

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The rate of leukocyte telomere shortening predicts mortality from cardiovascular disease in elderly men: a novel demonstration

Elissa S. Epel, Sharon Stein Merkin, Richard Cawthon, Elizabeth H. Blackburn, Nancy E. Adler, Mark J. Pletcher, Teresa E. Seeman,

https://doi.org/10.18632/aging.100007 pp 81—88

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Alterations in gene expression and sensitivity to genotoxic stress following HdmX or Hdm2 knockdown in human tumor cells harboring wild-type p53

Katherine Heminger, Michael Markey, Meldrick Mpagi, Steven J. Berberich,

https://doi.org/10.18632/aging.100008 pp 89—108

View Abstract PDF Full-Text How to Cite Special Collection on p53

SIRT6 stabilizes DNA-dependent Protein Kinase at chromatin for DNA double-strand break repair

Ronald A. McCord, Eriko Michishita, Tao Hong, Elisabeth Berber, Lisa D. Boxer, Rika Kusumoto, Shenheng Guan, Xiaobing Shi, Or Gozani, Alma L. Burlingame, Vilhelm A. Bohr, Katrin F. Chua,

https://doi.org/10.18632/aging.100011 pp 109—121

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Moderate expression of TRF2 in the hematopoietic system increases development of large cell blastic T-cell lymphomas

Sebastian Begemann, Francesco Galimi, Jan Karlseder,

https://doi.org/10.18632/aging.100015 pp 122—130

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Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density

Yong Pan, Gerald S. Shadel,

https://doi.org/10.18632/aging.100016 pp 131—145

View Abstract PDF Full-Text How to Cite Special Collection on Longevity and Rapamycin

Volume 1, Issue 1

Editorial

Aging: past, present and future

Mikhail V. Blagosklonny, Judith Campisi, David A. Sinclair,

Previews

Longevity regulation in flies: A role for p53

Lawrence A. Donehower,

Breathing lessons: Tor tackles the mitochondria

Toren Finkel,

Sirtuins at the Breaking Point: SIRT6 in DNA Repair

David B. Lombard,

Reviews

Apolipoprotein D in lipid metabolism and its functional implication in atherosclerosis and aging

German Perdomo, H. Henry Dong,

Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A

Phillip R. Musich, Yue Zou,

Research Papers

dSir2 and Dmp53 interact to mediate aspects of CR-dependent life span extension in D. melanogaster

Johannes H. Bauer, Siti Nur Sarah Morris, Chengyi Chang, Thomas Flatt, Jason G. Wood, Stephen L. Helfand,

Young adult donor bone marrow infusions into female mice postpone age-related reproductive failure and improve offspring survival

Kaisa Selesniemi, Ho-Joon Lee, Teruko Niikura, Jonathan L. Tilly,

Dual regulation of TERT activity through transcription and splicing by ΔNP63α

Esther Vorovich, Edward A. Ratovitski,

Fat accumulation in Caenorhabditis elegans triggered by the electrophilic lipid peroxidation product 4-Hydroxynonenal (4-HNE)

Sharda P. Singh, Maciej Niemczyk, Ludwika Zimniak, Piotr Zimniak,

The rate of leukocyte telomere shortening predicts mortality from cardiovascular disease in elderly men: a novel demonstration

Elissa S. Epel, Sharon Stein Merkin, Richard Cawthon, Elizabeth H. Blackburn, Nancy E. Adler, Mark J. Pletcher, Teresa E. Seeman,

Alterations in gene expression and sensitivity to genotoxic stress following HdmX or Hdm2 knockdown in human tumor cells harboring wild-type p53

Katherine Heminger, Michael Markey, Meldrick Mpagi, Steven J. Berberich,

SIRT6 stabilizes DNA-dependent Protein Kinase at chromatin for DNA double-strand break repair

Ronald A. McCord, Eriko Michishita, Tao Hong, Elisabeth Berber, Lisa D. Boxer, Rika Kusumoto, Shenheng Guan, Xiaobing Shi, Or Gozani, Alma L. Burlingame, Vilhelm A. Bohr, Katrin F. Chua,

Moderate expression of TRF2 in the hematopoietic system increases development of large cell blastic T-cell lymphomas

Sebastian Begemann, Francesco Galimi, Jan Karlseder,

Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density

Yong Pan, Gerald S. Shadel,

Table of Contents

Volume 1, Issue 1

Editorial

Mikhail V. Blagosklonny, Judith Campisi, David A. Sinclair,

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Previews

Lawrence A. Donehower,

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Toren Finkel,

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David B. Lombard,

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Reviews

German Perdomo, H. Henry Dong,

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Phillip R. Musich, Yue Zou,

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Research Papers

Johannes H. Bauer, Siti Nur Sarah Morris, Chengyi Chang, Thomas Flatt, Jason G. Wood, Stephen L. Helfand,

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Kaisa Selesniemi, Ho-Joon Lee, Teruko Niikura, Jonathan L. Tilly,

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Esther Vorovich, Edward A. Ratovitski,

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Sharda P. Singh, Maciej Niemczyk, Ludwika Zimniak, Piotr Zimniak,

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Elissa S. Epel, Sharon Stein Merkin, Richard Cawthon, Elizabeth H. Blackburn, Nancy E. Adler, Mark J. Pletcher, Teresa E. Seeman,

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Katherine Heminger, Michael Markey, Meldrick Mpagi, Steven J. Berberich,

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Ronald A. McCord, Eriko Michishita, Tao Hong, Elisabeth Berber, Lisa D. Boxer, Rika Kusumoto, Shenheng Guan, Xiaobing Shi, Or Gozani, Alma L. Burlingame, Vilhelm A. Bohr, Katrin F. Chua,

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Sebastian Begemann, Francesco Galimi, Jan Karlseder,

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Yong Pan, Gerald S. Shadel,

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Table of Contents