Volume 6, Issue 1

January 2014
pp 1—81

Table of Contents

Editorials

Hypothalamic Sirt1 in aging

Akiko Satoh, Shin-ichiro Imai,

https://doi.org/10.18632/aging.100627 pp 1—2

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Metabolic and immune integration in aging and age-related disease

Rebecca I. Clark, David W. Walker, Marc S. Dionne,

https://doi.org/10.18632/aging.100626 pp 3—4

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DAF-16 and PQM-1: Partners in longevity

Ronald G. Tepper, Coleen T. Murphy, Harmen J. Bussemaker,

https://doi.org/10.18632/aging.100628 pp 5—6

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Tissue-specific aging: a tale of functional asymmetry

Ismene Karakasilioti, George A. Garinis,

https://doi.org/10.18632/aging.100635 pp 7—8

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Research Papers

Serum profiling of healthy aging identifies phospho- and sphingolipid species as markers of human longevity

Ivan Montoliu, Max Scherer, Fiona Beguelin, Laeticia DaSilva, Daniela Mari, Stefano Salvioli, François-Pierre J. Martin, Miriam Capri, Laura Bucci, Rita Ostan, Paolo Garagnani, Daniela Monti, Elena Biagi, Patrizia Brigidi, Martin Kussmann, Serge Rezzi, Claudio Franceschi, Sebastiano Collino,

https://doi.org/10.18632/aging.100630 pp 9—25

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Clearance of senescent hepatocytes in a neoplastic-prone microenvironment delays the emergence of hepatocellular carcinoma

Fabio Marongiu, Maria Paola Serra, Marcella Sini, Fabrizio Angius, Ezio Laconi,

https://doi.org/10.18632/aging.100631 pp 26—34

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SIRT1-metabolite binding histone macroH2A1.1 protects hepatocytes against lipid accumulation

Valerio Pazienza, Michela Borghesan, Tommaso Mazza, Fareeba Sheedfar, Concetta Panebianco, Roger Williams, Gianluigi Mazzoccoli, Angelo Andriulli, Tomoko Nakanishi, Manlio Vinciguerra,

https://doi.org/10.18632/aging.100632 pp 35—47

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BMAL1-dependent regulation of the mTOR signaling pathway delays aging

Rohini V. Khapre, Anna A. Kondratova, Sonal Patel, Yuliya Dubrovsky, Michelle Wrobel, Marina P. Antoch, Roman V. Kondratov,

https://doi.org/10.18632/aging.100633 pp 48—57

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Indy gene variation in natural populations confers fitness advantage and life span extension through transposon insertion

Chen-Tseh Zhu, Chengyi Chang, Robert A. Reenan, Stephen L. Helfand,

https://doi.org/10.18632/aging.100634 pp 58—69

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Serines 440 and 467 in the Werner syndrome protein are phosphorylated by DNA-PK and affects its dynamics in response to DNA double strand breaks

Rika Kusumoto-Matsuo, Deblina Ghosh, Parimal Karmakar, Alfred May, Dale Ramsden, Vilhelm A. Bohr,

https://doi.org/10.18632/aging.100629 pp 70—81

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