Research Paper Volume 12, Issue 10 pp 9440—9446
Effects of passive smoking and its duration on the prevalence of prediabetes and type 2 diabetes mellitus in Chinese women
- 1 Department of Endocrinology, The Second Affiliated Hospital of Nanchang University, Nanchang 330000, Jiangxi, China
- 2 Department of Pulmonary and Critical Care Medicine, The Second People’s Hospital of Jingdezhen, Jingdezhen 100191, Jiangxi, China
- 3 School of Public Health, Nanchang University, Nanchang 330000, Jiangxi, China
Received: January 24, 2020 Accepted: April 18, 2020 Published: May 26, 2020
https://doi.org/10.18632/aging.103217How to Cite
Copyright © 2020 Wu et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Several studies have shown that active smoking is a risk factor for type 2 diabetes mellitus (T2DM). However, the effects of passive smoking on T2DM remains unknown. In this study, we investigated the effects of passive smoking and its duration on the prevalence of prediabetes and T2DM. According to passive smoking status, participants were divided into Group A (passive smokers) and Group B (controls). Furthermore, Group A was divided into three subgroups according to the duration of passive smoking: Group A1 (≤10 years), Group A2 (10–20 years), and Group A3 (>20 years). We found that the prevalence of impaired glucose tolerance (IGT) in Group A (26.6%), Group A2 (28%), and Group A3 (37.8%) was significantly higher than that in Group B (19.6%), and the prevalence gradually increased with an increase in the duration of passive smoking. Multiple logistic regression analysis showed that passive smoking for >10 years was a risk factor for impaired fasting glucose (IFG), IGT, and T2DM. Therefore, passive smoking not only increases the prevalence of IGT in a time-dependent manner, but also a risk factor for IFG, IGT, and T2DM when its duration is over 10 years.
Abbreviations
T2DM: type 2 diabetes mellitus; IGT: impaired glucose tolerance; IFG: impaired fasting glucose; BMI: body mass index; HDL: high-density lipoprotein; LDL: low-density lipoprotein; TC: total cholesterol; TG: triglyceride; FPG: fasting plasma glucose; 2hPG: 2-hour postprandial glucose; HbA1c: glycated hemoglobin A1c; IRS-1: insulin receptor substrate-1; OGTT: oral glucose tolerance test.