Research Paper Volume 1, Issue 2 pp 191—211

A screen of apoptosis and senescence regulatory genes for life span effects when over-expressed in Drosophila

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Figure 4. Effect of Baculovirus p35 over-expression on survival of adult flies. Baculovirus p35 transgenes inserted on the X chromosome, chromosome 2, and chromosome 3 were over-expressed during larval development or adult stage, as indicated. The life span assays were performed at 25°C. Open circles represent the no-drug control ("-"). Solid squares represent adults treated with drug ("A"). Grey triangles represent larvae on drug ("L"). Survival curves are plotted as a function of adult age in days. Median life span of each cohort is presented along with p value for log rank tests (in parentheses). (A, C, E, G) male flies. (B, D, F, H) female flies. (A,B) Control flies containing the driver and no target transgene. (C, D) Baculovirus p35 transgene on X chromosome. (E, F) Baculovirus p35 transgene on second chromosome. (G, H) Baculovirus p35 transgene on third chromosome.