Research Paper Volume 1, Issue 3 pp 303—315

Sod2 haploinsufficiency does not accelerate aging of telomere dysfunctional mice

Figure 4. (A) Kaplan Meyer survival curves for G3 mTerc-/-, Sod2+/- (n=58); G3 mTerc-/-, Sod2+/+ (n=38); mTerc-/-, Sod2+/- (n=31) and mTerc+, Sod2+/+ (n=34). (B) Survival curves for females G3 mTerc-/-, Sod2+/- (n=22); G3 mTerc-/-, Sod2+/+ (n=14); mTerc-/-, Sod2+/- (n=16) and mTerc+, Sod2+/+ (n=19). (C) Survival curves for males G3 mTerc-/-, Sod2+/- (n=36); G3 mTerc-/-, Sod2+/+ (n=24); mTerc-/-, Sod2+/- (n=15) and mTerc+, Sod2+/+ (n=15). Dot blots showing body weight of male (D) and female (E) mice throughout lifespan in the aging cohorts. Third order polynomial regression is shown as trendline. All mice were weighed monthly until death.