Research Paper Volume 2, Issue 4 pp 200—223

Mitochondrial ROS production correlates with, but does not directly regulate lifespan in drosophila

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Figure 6. Effects of the changes on mtDNA content on mtROS production and lifespan in new wild type strains of Drosophila melanogaster (DAHOR and ORDAH). (A) mtROS production, assayed as H2O2, (mean + SEM). a and b denote statistically significant differences between groups (ANOVA, p <0.05, n = 4-5 samples per group), m: male, f: female. (B) Survival curves. Combined data from two independent experiments using between 80-100 flies per group per experiment. Mean, maximum lifespans (d) were: ORDAH males (68, 76); ORDAH FEMALES (78, 87); DAHOR males (47,59); DAHOR females (87,92).