Figure 5. Hair cell loss in cochleae of Tg(Math1E-Aβ42Arc)1Lt/129 mice and control non-Tg siblings at age 8 months. (A) Cochleae of basal region staining with Alexa Fluor 488–phalloidin and DAPI. (B) Middle region of cochleae in non-Tg sibling. (C) Middle region of the cochlea in Tg(Math1E-Aβ42Arc)1Lt/129. (D) Basal region of the cochlea in non-Tg sibling. (E) Basal region of the cochlea in Tg(Math1E-Aβ42Arc)1Lt/129. OHCs, outer hair cells. The results of the OHCs count at each cochlea turns (% of hair cells loss) are shown in (F) (number of cochleae = 5, in each group). Middle-apex; middle to apex region. Basal; basal region. Data are the mean ± SEM. **P < 0.01.