Research Paper Volume 8, Issue 11 pp 3028—3044

Rpd3 interacts with insulin signaling in Drosophila longevity extension

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Figure 1. rpd3 reduction affects stress resistance and metabolism. (A,B) Reduced rpd3 levels increase stress resistance. Survival curves for male and female rpd3def/+ and control flies during starvation at age 10 (A) and 40 (B). (C-G) rpd3 reduction affects intermediary metabolism: Total levels of glucose (C), glycogen (D), trehalose (E), triglyceride (F) and protein (G) in rpd3def/+ and control male and female flies at age 10 and 40 days. (H) Weight of rpd3def and control flies used in C-G. Data are presented as means + SD (n=3, 30 flies per replicate. t test).