Research Paper Volume 9, Issue 10 pp 2163—2189

SIRT4 interacts with OPA1 and regulates mitochondrial quality control and mitophagy

Figure 11. Model summarizing the regulatory role of the SIRT4-OPA1 axis in mitochondrial quality control. OPA1, optic atrophy gene 1; ETC, electron transport chain; ROS, reactive oxygen species.