Sodium fluoride induces splenocyte autophagy via the mammalian targets of rapamycin (mTOR) signaling pathway in growing mice

Ping Kuang; Huidan Deng; Huan Liu; Hengmin Cui; Jing Fang; Zhicai Zuo; Junliang Deng; Yinglun Li; Xun Wang; Ling Zhao

doi:doi:10.18632/aging.101499

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Research Paper Volume 10, Issue 7 pp 1649—1665

Sodium fluoride induces splenocyte autophagy via the mammalian targets of rapamycin (mTOR) signaling pathway in growing mice

Figure 11. Changes of ULK1 mRNA and protein expression levels and Atg13 mRNA levels in the spleen at 21 and 42 days of the experiment. (A) The relative mRNA expression levels of ULK1. (B) The relative protein expression levels of ULK1. (C) The western blot assay of ULK1. (D) The relative mRNA expression levels of Atg13. Data are presented with the mean + standard deviation (n=8), *p < 0.05, compared with the control group; **p < 0.01, compared with the control group.