Research Paper Volume 10, Issue 11 pp 3185—3209

Identification of an energy metabolism-related signature associated with clinical prognosis in diffuse glioma

Figure 2. Identification of an energy metabolism-related signature by Cox proportional hazards model in TCGA cohort. (A) Venn diagram shows prognosis-related genes which are also differentially expressed between LGG and GBM. (B) Heat map of 420 energy metabolism-related genes correlated with patients’ OS. (C) Cross-validation for tuning parameter selection in the proportional hazards model. (D) Coefficient values for each of the 29 selected genes. (E) Heatmap of the 29 genes of the signature based on the risk score value.