Research Paper Volume 10, Issue 11 pp 3273—3282

Spindle pole body component 25 regulates stemness of prostate cancer cells

Figure 1. PrC with high SPC25 expression is associated with poor overall survival. (A-B) RT-qPCR for SPC25 mRNA levels in 40 PrC specimens and paired normal prostate tissue (NT), shown by mean ± SD (A), and by individual values (B). (C-D) ELISA for SPC25 protein levels in 40 PrC specimens and NT, shown by mean ± SD (C), and by individual values (D). (E) Immunostaining for SPC25 (fast red) in PrC and NT. (F) The 40 patients were followed-up for 5 years. The patients were classified into SPC25-high group (n=20) and SPC25-low group (n=20), based on the median value. Kaplan-Meier curves were plotted. *p<0.05. N=40. Scale bars are 100 µm.